New analytical methods developed at Baylor College of Medicine and collaborating institutions have increased our ...
Using high-resolution cryo-electron microscopy (cryo-em), researchers from Durham University, Jagiellonian University, and the John Innes Centre uncovered unprecedented detail of gyrase’s action on ...
New analytical methods developed at Baylor College of Medicine and collaborating institutions have increased our understanding of how bacteria manage DNA. The methods enabled researchers to uncover ...
Picture in your mind a traditional “landline” telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in ...
Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in ...
DNA gyrase, a bacterial type II topoisomerase, is instrumental in maintaining DNA supercoiling during replication and transcription. Owing to its absence in higher eukaryotes, it represents an ...
Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...
Bugworks Research India Pvt. Ltd. has identified oxazolidinone compounds acting as DNA gyrase and DNA topoisomerase IV (Escherichia coli) inhibitors reported to be useful for the treatment of ...