Enhancers are specified by distinct chromatin features that may contribute to the repertoire of epigenetic mechanisms responsible for cellular memory and cell type-specific gene expression. The ...
Ligand-dependent enhancer activation indirectly modulates non-target promoters in a chromatin domain
Ligand-driven enhancer activation selectively boosts target gene expression while indirectly repressing neighboring non-target genes, revealing dynamic and competitive regulation during early ...
In a 2010 Nature paper, researchers in the lab of neurobiologist Michael Greenberg at Harvard Medical School reported that enhancers can produce RNA. Working with cultured mouse neurons, the ...
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