Gene expression is an essential step in the translation of genotypes into phenotypes. However, little is known about the transcriptome architecture and the underlying genetic effects at the species ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA sequence loxP, which is its target. This vector allows the creation of ...

Targeted delivery of biomaterials in vivo has significantly improved therapeutic agent efficacy and safety in biomedicine by increasing accumulation at specific target sites and reducing off-target ...

A synthetic PAS (red) is inserted in the 5′ UTR of a transgene. Without ligand, the cleavage destroys the coding region of the mRNA, therefore, losing transgene expression. Ligand binding to the ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

QIAGEN QGEN recently expanded its QIAcuity digital PCR (dPCR) ecosystem with new gene expression solutions, enhanced ...

Mice and newts were applied to the one-step Cre-loxP organism creation technology by TAx9. In this study, the researchers succeeded in synthesizing a Cre-loxP integrated vector by placing a short DNA ...