Population geneticist Sohini Ramachandran uses computational approaches and develops new techniques to explore human genetic variation and diversity.

A new heritability-optimized scoring method called RovHer identifies the rare missense variants that explain the most genetic ...

Humans have between 20,000 and 25,000 genes that carry instructions for assembling the proteins that do the work of cells. Work led by St. Jude Children's Research Hospital found that children who ...

The pull toward a sugary drink or a plate of fries is often chalked up to willpower, but new genetic research suggests part of that craving is written into a person’s DNA. Analyzing the genes of ...

Protein–protein interaction (PPI) networks accurately map environmental perturbations to their molecular consequences in cells, yet the effects of natural genetic variation on PPIs remain poorly ...

Genetic canalization describes the capacity of developmental systems to produce consistent phenotypes despite genetic mutations or environmental fluctuations. This robustness is achieved through ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

In a comprehensive Genomic Press Invited Expert Review, researchers from the University of Haifa have synthesized cutting-edge findings on Prader-Willi syndrome (PWS), revealing how this complex ...

People from isolated parts of the U.K. could have variations in their genetic code that increase their chance of developing certain diseases, a study suggests. The most genetically distinct ...